Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target
Scrub typhus threatens one billion people in the Asia-Pacific area and cases have emerged outside this region.It is caused by infection with any of the multitude of strains of the bacterium Orientia tsutsugamushi.A vaccine that affords heterologous protection and a commercially-available molecular diagnostic assay are lacking.Herein, we determined